Novel Insights of Effects of Pregabalin on Neural Mechanisms of Intracortical Disinhibition in Physiopathology of Fibromyalgia: An Explanatory, Randomized, Double-Blind Crossover Study

Novel Insights of Effects of Pregabalin on Neural Mechanisms of Intracortical Disinhibition in Physiopathology of Fibromyalgia: An Explanatory, Randomized, Double-Blind Crossover Study

Background: The fibromyalgia (FM) physiopathology involves an intracortical excitability/inhibition imbalance as measured by transcranial magnetic stimulation measures (TMS). TMS measures provide an index that can help to understand how the basal neuronal plasticity state (i.e., levels of the serum...

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Bibliographic Details
Main Authors: Alícia Deitos, Matheus Dorigatti Soldatelli, Jairo Alberto Dussán-Sarria, Andressa Souza, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Human Neuroscience
Subjects:
fibromyalgia
cortical silent period
short intracortical inhibition
BDNF
S100B
Online Access:https://www.frontiersin.org/article/10.3389/fnhum.2018.00406/full

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https://www.frontiersin.org/article/10.3389/fnhum.2018.00406/full

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