Can ELABELA be a novel target in the treatment of chronic lymphocytic leukaemia?

Can ELABELA be a novel target in the treatment of chronic lymphocytic leukaemia?

Abstract Background It has been shown that bcl2, bcl-XL and mcl-1 protein levels are high in chronic lymphocytic leukemia cells, and resultantly, apoptosis does not occur chronic lymphocytic leukemia cells. Apelin and apela (ELABELA/ELA/Toddler) are two peptide ligands for a class A G-protein couple...

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Bibliographic Details
Main Authors: Didar Yanardag Acik, Mehmet Bankir, Filiz Alkan Baylan, Bilal Aygun
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
ELABELA
Apelinergic system
Chronic lymphocytic leukaemia
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12885-019-6325-6

Internet

http://link.springer.com/article/10.1186/s12885-019-6325-6

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