Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin

HMG-CoA reductase inhibitors or statins are effective in both the primary and secondary prevention of coronary heart disease, the extent of benefit being proportional to the reduction in low density lipoprotein (LDL) cholesterol achieved. Atorvastatin, a newly licensed compound, reportedly lowers LD...

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Bibliographic Details
Main Authors: R P Naoumova, S Dunn, L Rallidis, O Abu-Muhana, C Neuwirth, N B Rendell, G W Taylor, G R Thompson
Format: Article
Language:English
Published: Elsevier 1997-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520374320