QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects.

Obesity is a heritable trait caused by complex interactions between genes and environment, including diet. Gene-by-diet interactions are difficult to study in humans because the human diet is hard to control. Here, we used mice to study dietary obesity genes, by four methods. First, we bred 213 F2 m...

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Bibliographic Details
Main Authors: Cailu Lin, Maria L Theodorides, Amanda H McDaniel, Michael G Tordoff, Qinmin Zhang, Xia Li, Natalia Bosak, Alexander A Bachmanov, Danielle R Reed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726688?pdf=render