A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms.

The transmembrane protein 33 (TMEM33) was originally identified as an endoplasmic reticulum (ER) protein that influences the tubular structure of the ER and modulates intracellular calcium homeostasis. However, the role of TMEM33 in antiviral immunity in vertebrates has not been elucidated. In this...

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Bibliographic Details
Main Authors: Long-Feng Lu, Can Zhang, Zhuo-Cong Li, Xiao-Yu Zhou, Jing-Yu Jiang, Dan-Dan Chen, Yong-An Zhang, Feng Xiong, Fang Zhou, Shun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009317