Skeleton interoception regulates bone and fat metabolism through hypothalamic neuroendocrine NPY

Skeleton interoception regulates bone and fat metabolism through hypothalamic neuroendocrine NPY

The central nervous system regulates activity of peripheral organs through interoception. In our previous study, we have demonstrated that PGE2/EP4 skeleton interception regulate bone homeostasis. Here, we show that ascending skeleton interoceptive signaling downregulates expression of hypothalamic...

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Bibliographic Details
Main Authors: Xiao Lv, Feng Gao, Tuo Peter Li, Peng Xue, Xiao Wang, Mei Wan, Bo Hu, Hao Chen, Amit Jain, Zengwu Shao, Xu Cao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
skeleton interoception
bone formation
neuroendocrine
hypothalamus
neuropeptide y
prostaglandin E2
Online Access:https://elifesciences.org/articles/70324

Internet

https://elifesciences.org/articles/70324

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