Poly(dA:dT)-rich DNAs are highly flexible in the context of DNA looping.

Large-scale DNA deformation is ubiquitous in transcriptional regulation in prokaryotes and eukaryotes alike. Though much is known about how transcription factors and constellations of binding sites dictate where and how gene regulation will occur, less is known about the role played by the interveni...

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Bibliographic Details
Main Authors: Stephanie Johnson, Yi-Ju Chen, Rob Phillips
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795714?pdf=render