Phospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.

Phospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.

BACKGROUND: Phospholipase Cε (PLCε) is an effector of Ras and Rap small GTPases and expressed in non-immune cells. It is well established that PLCε plays an important role in skin inflammation, such as that elicited by phorbol ester painting or ultraviolet irradiation and contact dermatitis that is...

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Bibliographic Details
Main Authors: Tatsuya Nagano, Hironori Edamatsu, Kazuyuki Kobayashi, Nobuyuki Takenaka, Masatsugu Yamamoto, Naoto Sasaki, Yoshihiro Nishimura, Tohru Kataoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182471?pdf=render

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http://europepmc.org/articles/PMC4182471?pdf=render

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