Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers.

Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers.

INTRODUCTION: The angiogenic proteins angiopoietin (Ang)-1, Ang-2 and vascular endothelial growth factor (VEGF) are regulators of endothelial inflammation and integrity. Since platelets store large amounts of Ang-1 and VEGF, measurement of circulation levels of these proteins is sensitive to platele...

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Bibliographic Details
Main Authors: Judith Brouwers, Rintis Noviyanti, Rob Fijnheer, Philip G de Groot, Leily Trianty, Siti Mudaliana, Mark Roest, Din Syafruddin, Andre van der Ven, Quirijn de Mast
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3670845?pdf=render

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http://europepmc.org/articles/PMC3670845?pdf=render

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