Differential cytotoxicity but augmented IFN-γ secretion by NK cells after interaction with monocytes from humans, and those from wild type and myeloid specific COX-2 knockout mice

Differential cytotoxicity but augmented IFN-γ secretion by NK cells after interaction with monocytes from humans, and those from wild type and myeloid specific COX-2 knockout mice

The list of genes which augment NK cell function when knocked out in neighboring cells is increasing, and may point to the fundamental function of NK cells targeting cells with diminished capability to differentiate optimally since NK cells are able to target less differentiated cells, and aid in th...

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Bibliographic Details
Main Authors: Han-Ching eTseng, Aida eArasteh, Kawaljit eKaur, Anna eKozlowska, Paytsar eTopchyan, Anahid eJewett
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Immunology
Subjects:
IFN-gamma
NK
Cytotoxicity
LPS
COX-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00259/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00259/full

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