Self-adjuvanting glycopeptide conjugate vaccine against disseminated candidiasis.

Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface β-1, 2-mannotriose [β-(Man)(3)] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion of the C. albicans cytosolic/cell surface protein fru...

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Bibliographic Details
Main Authors: Hong Xin, Jonathan Cartmell, Justin J Bailey, Sebastian Dziadek, David R Bundle, Jim E Cutler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338514?pdf=render