The dynamics of DNA methylation covariation patterns in carcinogenesis.

Recently it has been observed that cancer tissue is characterised by an increased variability in DNA methylation patterns. However, how the correlative patterns in genome-wide DNA methylation change during the carcinogenic progress has not yet been explored. Here we study genome-wide inter-CpG corre...

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Bibliographic Details
Main Authors: Andrew E Teschendorff, Xiaoping Liu, Helena Caren, Steve M Pollard, Stephan Beck, Martin Widschwendter, Luonan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25010556/?tool=EBI