Hemodynamics Modify Collagen Deposition in the Early Embryonic Chicken Heart Outflow Tract

Hemodynamics Modify Collagen Deposition in the Early Embryonic Chicken Heart Outflow Tract

Blood flow is critical for normal cardiac development. Hemodynamic stimuli outside of normal ranges can lead to overt cardiac defects, but how early heart tissue remodels in response to altered hemodynamics is poorly understood. This study investigated changes in tissue collagen in response to hemod...

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Bibliographic Details
Main Authors: Monique Y. Rennie, Stephanie Stovall, James P. Carson, Michael Danilchik, Kent L. Thornburg, Sandra Rugonyi
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cardiac development
mechanotransduction
tissue remodeling
congenital heart disease
heart malformation
Online Access:https://www.mdpi.com/2308-3425/4/4/24

Internet

https://www.mdpi.com/2308-3425/4/4/24

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