Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism

In some parasites, membrane-bound pyrophosphatases, which couple proton and sodium ion transport across the membrane, are important for infectivity. Here, the authors report crystal structures of these proteins alongside biophysical analyses that allow them to propose a model for how the coupling is...

Full description

Bibliographic Details
Main Authors: Kun-Mou Li, Craig Wilkinson, Juho Kellosalo, Jia-Yin Tsai, Tommi Kajander, Lars J. C. Jeuken, Yuh-Ju Sun, Adrian Goldman
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13596