Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2

Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2

Background/Aims: Inherited, autosomal dominant spinocerebellar ataxia type 11 (SCA11) is caused by loss of function mutations of TTBK2 (tau tubulin kinase 2). Mutations observed in patients with SCA11 include truncated TTBK2(450). The present study explored the possibility that TTBK2 influences the...

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Bibliographic Details
Main Authors: Kristina Nieding, Veronika Matschke, Sven G. Meuth, Florian Lang, Guiscard Seebohm, Nathalie Strutz-Seebohm
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Spinocerebellar ataxia type 11
Neuroexcitotoxicity
Kainate receptor
Rab5
Online Access:http://www.karger.com/Article/FullText/447847

Internet

http://www.karger.com/Article/FullText/447847

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