Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial

Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial

Abstract Treatment of severe Coronavirus Disease 2019 (COVID-19) is challenging. We performed a phase 2 trial to assess the efficacy and safety of human umbilical cord-mesenchymal stem cells (UC-MSCs) to treat severe COVID-19 patients with lung damage, based on our phase 1 data. In this randomized,...

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Bibliographic Details
Main Authors: Lei Shi, Hai Huang, Xuechun Lu, Xiaoyan Yan, Xiaojing Jiang, Ruonan Xu, Siyu Wang, Chao Zhang, Xin Yuan, Zhe Xu, Lei Huang, Jun-Liang Fu, Yuanyuan Li, Yu Zhang, Wei-Qi Yao, Tianyi Liu, Jinwen Song, Liangliang Sun, Fan Yang, Xin Zhang, Bo Zhang, Ming Shi, Fanping Meng, Yanning Song, Yongpei Yu, Jiqiu Wen, Qi Li, Qing Mao, Markus Maeurer, Alimuddin Zumla, Chen Yao, Wei-Fen Xie, Fu-Sheng Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00488-5

Internet

https://doi.org/10.1038/s41392-021-00488-5

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