Identification and Isolation of Cardiac Fibroblasts From the Adult Mouse Heart Using Two-Color Flow Cytometry

Identification and Isolation of Cardiac Fibroblasts From the Adult Mouse Heart Using Two-Color Flow Cytometry

Background: Cardiac fibroblasts represent a main stromal cell type in the healthy myocardium. Activation of cardiac fibroblasts has been implicated in the pathogenesis of many heart diseases. Profibrotic stimuli activate fibroblasts, which proliferate and differentiate into pathogenic myofibroblasts...

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Bibliographic Details
Main Authors: Mara Stellato, Marcin Czepiel, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiac fibroblast
collagen I
gp38/podoplanin
FACS sorting
flow cytometry
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2019.00105/full

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https://www.frontiersin.org/article/10.3389/fcvm.2019.00105/full

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