Identification of Trenbolone Metabolites Using Hydrogen Isotope Ratio Mass Spectrometry and Liquid Chromatography/High Accuracy/High Resolution Mass Spectrometry for Doping Control Analysis

Identification of Trenbolone Metabolites Using Hydrogen Isotope Ratio Mass Spectrometry and Liquid Chromatography/High Accuracy/High Resolution Mass Spectrometry for Doping Control Analysis

Trenbolone is a synthetic anabolic-androgenic steroid, which has been misused for performance enhancement in sports. The detection of trenbolone doping in routine sports drug testing programs is complex as methods utilizing gas chromatography/mass spectrometry are complicated by unspecific derivatiz...

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Bibliographic Details
Main Authors: Marlen Putz, Thomas Piper, Mario Thevis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Chemistry
Subjects:
gas chromatography thermal conversion isotope ratio mass spectrometry (GC-TC-IRMS)
liquid chromatography high resolution mass spectrometry (LC-HRMS)
human metabolism
steroids
phase-II conjugates
pseudo MS3 product ion mass spectra
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00435/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00435/full

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