The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth

The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth

Tumors are characterized by the presence of malignant and non-malignant cells, such as immune cells including macrophages, which are preponderant. Macrophages impact the efficacy of chemotherapy and may lead to drug resistance. In this context and based on our previous work, we investigated the abil...

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Bibliographic Details
Main Authors: Mélanie Rose, Marie Duhamel, Soulaimane Aboulouard, Firas Kobeissy, Emilie Le Rhun, Annie Desmons, Dominique Tierny, Isabelle Fournier, Franck Rodet, Michel Salzet
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
macrophages
immunotherapy
temozolomide
proprotein convertases
mass spectrometry-based proteomic
glioma
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300267

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http://www.sciencedirect.com/science/article/pii/S2372770520300267

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