Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation

Fluctuating hormone levels, such as estradiol might underlie the difference in the prevalence of psychiatric disorders observed in women vs. men. Estradiol exert its effects primarily through binding on the two classical estrogen receptor subtypes, alpha (ERα) and beta (ERβ). Both receptors have bee...

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Bibliographic Details
Main Authors: Polymnia Georgiou, Panos Zanos, Carleigh E. Jenne, Todd D. Gould
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00081/full