A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation

A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation

Abstract Background Cerebrospinal fluid (CSF) neurofilament light (NfL) is a reliable marker of neuro-axonal damage in different neurological disorders that is related to disease severity. To date, all recent studies performed in human CSF have used the same enzyme-linked immunosorbent assay (ELISA)...

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Bibliographic Details
Main Authors: Lorenzo Gaetani, Kina Höglund, Lucilla Parnetti, Fani Pujol-Calderon, Bruno Becker, Paolo Eusebi, Paola Sarchielli, Paolo Calabresi, Massimiliano Di Filippo, Henrik Zetterberg, Kaj Blennow
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Alzheimer’s Research & Therapy
Subjects:
Neurofilament light
ELISA
Cerebrospinal fluid
Multiple sclerosis
Clinically isolated syndrome
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13195-018-0339-1

Internet

http://link.springer.com/article/10.1186/s13195-018-0339-1

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