The Cell Biology of Tau Secretion

The progressive accumulation and spread of misfolded tau protein in the nervous system is the hallmark of tauopathies, progressive neurodegenerative diseases with only symptomatic treatments available. A growing body of evidence suggests that spreading of tau pathology can occur via cell-to-cell tra...

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Bibliographic Details
Main Authors: Maria Merezhko, Riikka-Liisa Uronen, Henri J. Huttunen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.569818/full