HIV DNA Vaccine: Stepwise Improvements Make a Difference

HIV DNA Vaccine: Stepwise Improvements Make a Difference

Inefficient DNA delivery methods and low expression of plasmid DNA have been major obstacles for the use of plasmid DNA as vaccine for HIV/AIDS. This review describes successful efforts to improve DNA vaccine methodology over the past ~30 years. DNA vaccination, either alone or in combination with o...

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Bibliographic Details
Main Authors: Barbara K. Felber, Antonio Valentin, Margherita Rosati, Cristina Bergamaschi, George N. Pavlakis
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Vaccines
Subjects:
macaque
cytokine
plasmid
electroporation
immunogenicity
vaccination
DNA delivery
DNA expression
Online Access:http://www.mdpi.com/2076-393X/2/2/354

Internet

http://www.mdpi.com/2076-393X/2/2/354

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