New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists

Rüdiger HardelandJohann Friedrich Blumenbach Institute of Zoology and Anthropology, University of Göttingen, GermanyAbstract: Hypnotic effects of melatonin and melatoninergic drugs are mediated via MT1 and MT2 receptors, especially those in the circadian pacemaker, the supr...

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Bibliographic Details
Main Author: Rüdiger Hardeland
Format: Article
Language:English
Published: Dove Medical Press 2009-06-01
Series:Neuropsychiatric Disease and Treatment
Online Access:http://www.dovepress.com/new-approaches-in-the-management-of-insomnia-weighing-the-advantages-o-a3246