Mechanisms of Mutational Robustness in Transcriptional Regulation

Robustness is the invariance of a phenotype in the face of environmental or genetic change. The phenotypes produced by transcriptional regulatory circuits are gene expression patterns that are to some extent robust to mutations. Here we review several causes of this robustness. They include robustne...

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Bibliographic Details
Main Authors: Joshua L. Payne, Andreas eWagner
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00322/full