Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes
Centrosome overduplication or amplification has been observed in many human cancers and in premalignant tissue, but the mechanisms leading to such centrosome aberrations are not fully understood. We previously showed that abnormal mitotic cells with supernumerary centrosomes increase with replicativ...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2012-01-01
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| Series: | Oxidative Medicine and Cellular Longevity |
| Online Access: | http://dx.doi.org/10.1155/2012/217594 |