The paradox of cancer genes in non-malignant conditions: implications for precision medicine

Abstract Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures. Intriguingly, rapidly emerging data indicate that altered genes representing oncogenic drivers can also be found i...

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Bibliographic Details
Main Authors: Jacob J. Adashek, Shumei Kato, Scott M. Lippman, Razelle Kurzrock
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-020-0714-y