Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells

Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells

Khuloud Bajbouj,1 Jasmin Shafarin,1 Mawieh Hamad1,21Sharjah Institute for Medical Research, Sharjah, United Arab Emirates; 2Department of Medical Laboratory Sciences, University of Sharjah, Sharjah, United Arab EmiratesIntroduction: Increased iron content in cancer cells is associated with resistanc...

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Bibliographic Details
Main Authors: Bajbouj K, Shafarin J, Hamad M
Format: Article
Language:English
Published: Dove Medical Press 2019-05-01
Series:Cancer Management and Research
Subjects:
Cancer
doxorubicin
estrogen
iron
hepcidin
ferroportin
apoptosis.
Online Access:https://www.dovepress.com/estrogen-dependent-disruption-of-intracellular-iron-metabolism-augment-peer-reviewed-article-CMAR

Internet

https://www.dovepress.com/estrogen-dependent-disruption-of-intracellular-iron-metabolism-augment-peer-reviewed-article-CMAR

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