Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1

<p>Abstract</p> <p>Background</p> <p>A number of prostaglandins (PGs) sensitize dorsal root ganglion (DRG) neurons and contribute to inflammatory hyperalgesia by signaling through specific G protein-coupled receptors (GPCRs). One mechanism whereby PGs sensitize these ne...

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Bibliographic Details
Main Authors: Cavanaugh Eric J, Montana Michael C, Young Timothy J, Heuermann Robert J, Dhaka Ajay, Cruz-Orengo Lillian, Kim Donghee, Story Gina M
Format: Article
Language:English
Published: SAGE Publishing 2008-07-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/4/1/30