Transcription Factor Egr1 is Involved in High Glucose-Induced Proliferation and Fibrosis in Rat Glomerular Mesangial Cells

Transcription Factor Egr1 is Involved in High Glucose-Induced Proliferation and Fibrosis in Rat Glomerular Mesangial Cells

Backgroud: Diabetic nephropathy is one of the most frequent causes of end-stage renal disease and is associated with proliferation of glomerular mesangial cells (MCs) and excessive production of the extracellular matrix (ECM). Several studies have shown that early growth response factor 1 (Egr1) pla...

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Bibliographic Details
Main Authors: Dan Wang, Mei-Ping Guan, Zong-Ji Zheng, Wen-Qi Li, Fu-Ping Lyv, Ruo-Yu Pang, Yao-Ming Xue
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Egr1
Diabetic nephropathy
TGF-β1
Mesangial cells
Extracellular matrix
Online Access:http://www.karger.com/Article/FullText/430177

Internet

http://www.karger.com/Article/FullText/430177

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