The Murine Factor H-Related Protein FHR-B Promotes Complement Activation

The Murine Factor H-Related Protein FHR-B Promotes Complement Activation

Factor H-related (FHR) proteins consist of varying number of complement control protein domains that display various degrees of sequence identity to respective domains of the alternative pathway complement inhibitor factor H (FH). While such FHR proteins are described in several species, only human...

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Bibliographic Details
Main Authors: Marcell Cserhalmi, Ádám I. Csincsi, Zoltán Mezei, Anne Kopp, Mario Hebecker, Barbara Uzonyi, Mihály Józsi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
complement deregulation
C-reactive protein
factor H
factor H-related protein
endothelial cell
extracellular matrix
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01145/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01145/full

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