M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening

M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case fatality rates of approximately 30%. There are few treatment options for SFTSV infection. SFTSV RNA synthesis is conducted using a virus-encoded complex with...

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Bibliographic Details
Main Authors: Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta, Masayuki Saijo, Hideki Tani
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
SFTSV
minigenome assay
antivirals
antiviral screening
favipiravir
ribavirin
Online Access:https://www.mdpi.com/1999-4915/13/6/1061

Internet

https://www.mdpi.com/1999-4915/13/6/1061

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