Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer

Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer

Abstract Background Circulating tumor cells (CTCs) represent a temporal “snapshot” of a patient’s cancer and changes that occur during disease evolution. There is an extensive literature studying CTCs in breast cancer patients, and particularly in those with metastatic disease. In parallel, there is...

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Bibliographic Details
Main Authors: Vishnu C. Ramani, Clementine A. Lemaire, Melanie Triboulet, Kerriann M. Casey, Kyra Heirich, Corinne Renier, José G. Vilches-Moure, Rakhi Gupta, Aryana M. Razmara, Haiyu Zhang, George W. Sledge, Elodie Sollier, Stefanie S. Jeffrey
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Breast Cancer Research
Subjects:
Circulating tumor cells (CTCs)
Epithelial-mesenchymal transition (EMT)
Liquid biopsy
NOD scid gamma (NSG)
Patient-derived orthotopic xenograft (PDOX)
Triple-negative breast cancer (TNBC)
Online Access:http://link.springer.com/article/10.1186/s13058-019-1182-4

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http://link.springer.com/article/10.1186/s13058-019-1182-4

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