Expanding the Spectrum of Pancreatic Cancers Responsive to Vesicular Stomatitis Virus-Based Oncolytic Virotherapy: Challenges and Solutions

Expanding the Spectrum of Pancreatic Cancers Responsive to Vesicular Stomatitis Virus-Based Oncolytic Virotherapy: Challenges and Solutions

Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with poor prognosis and a dismal survival rate, expected to become the second leading cause of cancer-related deaths in the United States. Oncolytic virus (OV) is an anticancer approach that utilizes replication-competent viruses to...

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Bibliographic Details
Main Authors: Molly C. Holbrook, Dakota W. Goad, Valery Z. Grdzelishvili
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
oncolytic virus
virotherapy
pancreatic cancer
pancreatic ductal adenocarcinoma
vesicular stomatitis virus
Online Access:https://www.mdpi.com/2072-6694/13/5/1171

Internet

https://www.mdpi.com/2072-6694/13/5/1171

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