The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?

Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid-laden macrophages (LLMs) within the airway may indicate aspiration secondary to GOR. The proposed mechanism, that lipid droplets from undigested or partial...

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Bibliographic Details
Main Authors: Yvette A. Hayman, Laura R. Sadofsky, James D. Williamson, Simon P. Hart, Alyn H. Morice
Format: Article
Language:English
Published: European Respiratory Society 2017-03-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/3/1/00026-2016.full