Next-generation cDNA screening for oncogene and resistance phenotypes.

Next-generation cDNA screening for oncogene and resistance phenotypes.

There is a pressing need for methods to define the functional relevance of genetic alterations identified by next-generation sequencing of cancer specimens. We developed new approaches to efficiently construct full-length cDNA libraries from small amounts of total RNA, screen for transforming and re...

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Bibliographic Details
Main Authors: Nobuaki Shindoh, Akinori Yoda, Yuka Yoda, Timothy J Sullivan, Oliver Weigert, Andrew A Lane, Nadja Kopp, Liat Bird, Scott J Rodig, Edward A Fox, David M Weinstock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492311?pdf=render

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http://europepmc.org/articles/PMC3492311?pdf=render

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