PROGNOSTIC VALUE OF VHL GENE ALTERATION IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

PROGNOSTIC VALUE OF VHL GENE ALTERATION IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

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Objective: to estimate the rate, predictive and prognostic value of VHL gene alterations in the population of patients with sporadic metastatic renal cell carcinoma (mRCC).Subjects and methods. Paraffin embedded tumor tissue blocks were available from 88 patients with mRCC who had undergone antitumo...

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Bibliographic Details
Main Authors: D. A. Nosov, E. S. Yakovleva, M. Yu. Fedyanin, D. A. Chekini, M. N. Sinitsyna, N. A. Savelov, D. S. Mikhailenko, D. V. Zaletayev, L. N. Lyubchenko, S. A. Tjulandin
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Onkourologiâ
Subjects:
metastatic renal cell carcinoma
targeted therapy
vhl gene mutation
promoter hypermethylation
Online Access:https://oncourology.abvpress.ru/oncur/article/view/233

Internet

https://oncourology.abvpress.ru/oncur/article/view/233

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