Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice

Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice

Alcoholism is a complex behavioral disorder characterized by loss of control in limiting intake, and progressive compulsion to seek and consume ethanol. Prior studies have suggested that the characteristic behaviors associated with escalation of drug use are caused, at least in part, by ethanol-evok...

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Bibliographic Details
Main Authors: Megan A. O’Brien, Rory M. Weston, Nihar U. Sheth, Steven Bradley, John Bigbee, Ashutosh Pandey, Robert W. Williams, Jennifer T. Wolstenholme, Michael F. Miles
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Genetics
Subjects:
synaptic
mRNA trafficking
RNAseq
exon utilization
ethanol
sensitization
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00402/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00402/full

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