A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon beta (IFN-beta) gene expression. We demonstrate here that NSs interacts with the host protein SAP30, which belongs to Sin3A/NCoR/HDACs repressor complexes and interacts with...

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Bibliographic Details
Main Authors: Nicolas Le May, Zeyni Mansuroglu, Psylvia Léger, Thibaut Josse, Guillaume Blot, Agnès Billecocq, Ramon Flick, Yves Jacob, Eliette Bonnefoy, Michèle Bouloy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18225953/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18225953/?tool=EBI

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