PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654Summary

PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654Summary

Background & Aims: Identification and validation of new functionally relevant and pharmacologically actionable targets for pancreatic ductal adenocarcinoma (PDAC) remains a great challenge. Premalignant acinar cell reprogramming (acinar-to-ductal metaplasia [ADM]) is a precursor of pancreatic in...

Full description

Bibliographic Details
Main Authors: Chenxi Gao, Guangming Chen, Dennis Han Zhang, Judy Zhang, Shih-Fan Kuan, Wenhuo Hu, Farzad Esni, Xuan Gao, Jun-Lin Guan, Edward Chu, Jing Hu
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300918

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X19300918

Similar Items