Autoimmune-Mediated Retinopathy in CXCR5-Deficient Mice as the Result of Age-Related Macular Degeneration Associated Proteins Accumulation

Previous research has shown that CXCR5−/− mice develop retinal degeneration (RD) with age, a characteristic related to age macular degeneration (AMD). RD in these mice is not well-understood, and in this study, we sought to characterize further the RD phenotype and to gain mechanistic insights into...

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Bibliographic Details
Main Authors: Anton Lennikov, Madhu Sudhana Saddala, Anthony Mukwaya, Shibo Tang, Hu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
AMD
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01903/full