The hypervariable amino-terminus of P1 protease modulates potyviral replication and host defense responses.

The replication of many RNA viruses involves the translation of polyproteins, whose processing by endopeptidases is a critical step for the release of functional subunits. P1 is the first protease encoded in plant potyvirus genomes; once activated by an as-yet-unknown host factor, it acts in cis on...

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Bibliographic Details
Main Authors: Fabio Pasin, Carmen Simón-Mateo, Juan Antonio García
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3946448?pdf=render