On the History and Applications of Congenic Strains in <i>Cryptococcus</i> Research

Congenic strains have been utilized in numerous model organisms to determine the genetic underpinning of various phenotypic traits. Congenic strains are usually derived after 10 backcrosses to a recipient parent, at which point they are 99.95% genetically identical to the parental strain. In recent...

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Bibliographic Details
Main Authors: Benjamin J. Chadwick, Xiaorong Lin
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/9/750