Factor VIII Intron 22 Inversion in Severe Hemophilia A Patients in Palestine

Background. Hemophilia A is an X-linked recessive bleeding disorder caused by mutations in FVIII gene with an incidence of 1 in 5,000 to 10,000 live born males. The Inv22 mutation is a major cause of the disease worldwide, accounting for up to 40%–50% of severe FVIII mutations. The aim of the presen...

Full description

Bibliographic Details
Main Authors: Caesar Mahmoud Abu Arra, Fekri Samarah, Nael Sudqi Abu Hasan
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2020/3428648