Factor VIII Intron 22 Inversion in Severe Hemophilia A Patients in Palestine
Background. Hemophilia A is an X-linked recessive bleeding disorder caused by mutations in FVIII gene with an incidence of 1 in 5,000 to 10,000 live born males. The Inv22 mutation is a major cause of the disease worldwide, accounting for up to 40%–50% of severe FVIII mutations. The aim of the presen...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | Scientifica |
Online Access: | http://dx.doi.org/10.1155/2020/3428648 |