Topical Antinociceptive Effect of Vanillosmopsis arborea Baker on Acute Corneal Pain in Mice

This study aimed to assess the possible topical antinociceptive activity of Vanillosmopsis arborea Baker essential oil (EOVA) and to clarify the underlying mechanism, using the acute model of chemical (eye wiping) nociception in mice. EOVA (25 to 200 mg/kg; p.o. and topical) evidenced significant an...

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Bibliographic Details
Main Authors: Laura Hévila Inocêncio Leite, Gerlânia de Oliveira Leite, Thales Silva Coutinho, Severino Denício Gonçalves de Sousa, Renata Souza Sampaio, José Galberto Martins da Costa, Irwin Rose Alencar de Menezes, Adriana Rolim Campos
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/708636