Oral direct renin inhibitor aliskiren reduces in vivo oxidative stress and serum matrix metalloproteinase-2 levels in patients with permanent atrial fibrillation

Oral direct renin inhibitor aliskiren reduces in vivo oxidative stress and serum matrix metalloproteinase-2 levels in patients with permanent atrial fibrillation

We aimed to determine the effects of the oral direct renin inhibitor aliskiren on in vivo oxidative stress in atrial fibrillation (AF) patients. In this study, 150 mg oral direct renin inhibitor aliskiren was administered once daily to 12 permanent AF patients. Aliskiren significantly reduced urinar...

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Bibliographic Details
Main Authors: Yoshizumi Takei, MD, Minoru Ichikawa, MD, PhD, Yoshiyuki Kijima, MD, PhD
Format: Article
Language:English
Published: Wiley 2015-04-01
Series:Journal of Arrhythmia
Subjects:
Atrial fibrillation
Free radicals
Matrix metalloproteinase
Online Access:http://www.sciencedirect.com/science/article/pii/S1880427614001252

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http://www.sciencedirect.com/science/article/pii/S1880427614001252

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