Intravenous delivery of targeted liposomes to amyloid-β pathology in APP/PSEN1 transgenic mice.

Intravenous delivery of targeted liposomes to amyloid-β pathology in APP/PSEN1 transgenic mice.

Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer's disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents...

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Bibliographic Details
Main Authors: Eric A Tanifum, Indrani Dasgupta, Mayank Srivastava, Rohan C Bhavane, Li Sun, John Berridge, Hoda Pourgarzham, Rashmi Kamath, Gabriela Espinosa, Stephen C Cook, Jason L Eriksen, Ananth Annapragada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119043/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119043/?tool=EBI

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