Mucosal adjuvant activity of IL-2 presenting spores of bacillus subtilis in a murine model of Helicobacter pylori vaccination.

The endospores of Bacillus subtilis are now widely used as a platform for presentation of heterologous proteins and due to their safety record and high resistance to harsh environmental conditions can be considered as potential vehicles for oral vaccination. In this research we show that recombinant...

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Bibliographic Details
Main Authors: Krzysztof Hinc, Małgorzata Stasiłojć, Iwona Piątek, Grażyna Peszyńska-Sularz, Rachele Isticato, Ezio Ricca, Michał Obuchowski, Adam Iwanicki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990602?pdf=render