Search for New Aggregable Fragments of Human Insulin

Search for New Aggregable Fragments of Human Insulin

In this study, three independent methods were used to identify short fragment of both chains of human insulin which are prone for aggregation. In addition, circular dichroism (CD) research was conducted to understand the progress of aggregation over time. The insulin fragments (deca- and pepta-pepti...

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Bibliographic Details
Main Authors: Monika Swiontek, Justyna Fraczyk, Joanna Wasko, Agata Chaberska, Lukasz Pietrzak, Zbigniew J. Kaminski, Lukasz Szymanski, Slawomir Wiak, Beata Kolesinska
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Molecules
Subjects:
Aggregation
amyloid deposits
amyloid-like fiber formation
diabetes
SPPS
triazine coupling reagents
Online Access:https://www.mdpi.com/1420-3049/24/8/1600

Internet

https://www.mdpi.com/1420-3049/24/8/1600

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