A `one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer

A `one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer

Cancer cell phenotypes evolve during a tumor's treatment. In some cases, tumor cells acquire cancer stem cell-like (CSL) traits such as resistance to chemotherapy and diminished differentiation; therefore, targeting these cells may be therapeutically beneficial. In this study we show that in pr...

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Bibliographic Details
Main Authors: Feng Chi, Jiayi Liu, Samuel W. Brady, Patrick A. Cosgrove, Aritro Nath, Jasmine A. McQuerry, Sumana Majumdar, Philip J. Moos, Jeffrey T. Chang, Michael Kahn, Andrea H. Bild
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Subjects:
CSL
Chemotherapy
HDAC
Single-cell RNA-Seq
MYC
Chemoresistance
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304381

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http://www.sciencedirect.com/science/article/pii/S1936523320304381

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